A,B,D,F-tetrasubstituted β-cyclodextrin as artificial channel compound

As a channel forming compound, β-cyclodextrin having four hydrophobic tails and three metal binding sites, 1, A,C,D,F,-tetra-6-(6-n-butyrylamino-n-hexylsulfenyl)-β-cyclodextrin] was synthesized as a “half channel”. Artificial liposome modified with 1 transported Co⁺⁺ efficiently with the rate, 4.5 × 10^?4sec^?1 for 55 μM 1, much faster tahn the rate for the unmodified liposome.