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Structural conformation of biomolecules released from temperature-sensitive composite polymer particles – a study by circular dichroism
Authors:Hasan Ahmad  M. Okubo  Y. O. Kamatari  H. Minami
Affiliation:(1) Department of Chemical Science and Engineering, Faculty of Engineering Kobe University, Rokko, Nada Kobe 657-8501, Japan, JP
Abstract:
A conformational study of the biomolecules released from submicron- and micron-sized temperature-sensitive composite polymer particles by decreasing the temperature from 40 to 25 °C was done with circular dichroism and the results were compared with those of the native biomolecules. In almost all cases the biomolecules released retained their native conformational states. Received: 10 April 2001 Accepted: 13 June 2001
Keywords:Temperature-sensitive  Adsorption  Biomolecules  Conformation
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