Structural conformation of biomolecules released from temperature-sensitive composite polymer particles – a study by circular dichroism |
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| Authors: | Hasan Ahmad M Okubo Y O Kamatari H Minami |
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| Institution: | (1) Department of Chemical Science and Engineering, Faculty of Engineering Kobe University, Rokko, Nada Kobe 657-8501, Japan, JP |
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| Abstract: | A conformational study of the biomolecules released from submicron- and micron-sized temperature-sensitive composite polymer
particles by decreasing the temperature from 40 to 25 °C was done with circular dichroism and the results were compared with
those of the native biomolecules. In almost all cases the biomolecules released retained their native conformational states.
Received: 10 April 2001 Accepted: 13 June 2001 |
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| Keywords: | Temperature-sensitive Adsorption Biomolecules Conformation |
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