Unlocking the N2 Selectivity of Benzotriazoles: Regiodivergent and Highly Selective Coupling of Benzotriazoles with Allenes |
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| Authors: | Kun Xu Niels Thieme Prof?Dr Bernhard Breit |
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| Institution: | Institut für Organische Chemie, Albert‐Ludwigs‐Universit?t Freiburg, Albertstrasse 21, 79104 Freiburg im Breisgau (Germany) |
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| Abstract: | The rhodium‐catalyzed, highly N2‐ and N1‐selective coupling of benzotriazoles with allenes is reported. The exceptionally high N2 and N1 selectivities were achieved by using a rhodium(I)/DPEphos and rhodium(I)/JoSPOphos catalyst, respectively. This method permits the atom‐economic synthesis of valuable branched N2‐ and N1‐allylated benzotriazole derivatives and allows for preliminary studies of their reactivity. |
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| Keywords: | allenes allylic compounds benzotriazoles heterocyles homogeneous catalysis |
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