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Transient Substrate‐Induced Catalyst Formation in a Dynamic Molecular Network |
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| Authors: | Hugo Fanlo‐Virgós Dr. Andrea‐Nekane R. Alba Saleh Hamieh Mathieu Colomb‐Delsuc Prof. Dr. Sijbren Otto |
| Affiliation: | Centre for Systems Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen (The Netherlands) http://www.otto‐lab.com |
| Abstract: | In biology enzyme concentrations are continuously regulated, yet for synthetic catalytic systems such regulatory mechanisms are underdeveloped. We now report how a substrate of a chemical reaction induces the formation of its own catalyst from a dynamic molecular network. After complete conversion of the substrate, the network disassembles the catalyst. These results open up new opportunities for controlling catalysis in synthetic chemical systems. |
| Keywords: | aza‐Cope rearrangement combinatorial chemistry dynamic molecular networks supramolecular chemistry systems chemistry |