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Effects of allylic and homoallylic substituents on the ring closing metathesis reaction used to synthesise simplified eleuthesides |
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| Authors: | Lorenzo CaggianoDamiano Castoldi Raphael BeumerPau Bayón Joachim TelserCesare Gennari |
| Institution: | Dipartimento di Chimica Organica e Industriale, Centro di Eccellenza C.I.S.I., Universita’ di Milano, Istituto CNR di Scienze e Tecnologie Molecolari, via Venezian 21, I-20133 Milano, Italy |
| Abstract: | During the course of our synthetic studies towards simplified eleuthesides, we have found that p-methoxyphenyl (PMP) protected allylic alcohols are compatible with the RCM reaction and can give better yields than the corresponding free allylic alcohols. |
| Keywords: | ring closing metathesis protective groups p-methoxyphenyl (PMP) antitumour compounds |
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