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Trifluoromethylated amino alcohols as chiral ligands for highly enantioselective Reformatsky reaction |
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| Authors: | Yasuyuki FujiwaraToshimasa Katagiri Kenji Uneyama |
| Institution: | Department of Applied Chemistry, Faculty of Engineering, Okayama University, Okayama 700-8530, Japan |
| Abstract: | The enantioselective Reformatsky reaction of PhCHO was achieved by the use of trifluoromethylated amino alcohols as chiral ligands to afford the corresponding optically active β-hydroxy ester with up to 90% ee. |
| Keywords: | trifluoromethylated amino alcohol chiral ligand enantioselective Reformatsky reaction |
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