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Organically modified xerogels as novel tailor-made supports for covalent immobilisation of enzymes (penicillin G acylase)
Authors:Alessandra BassoLuigi De Martin  Cynthia EbertLucia Gardossi  Paolo LindaFabrizio Sibilla
Institution:Dipartimento di Scienze Farmaceutiche, Università degli Studi, Piazzale Europa 1, 34127 Trieste, Italy
Abstract:A novel application of organically modified silicates for covalent immobilisation of penicillin G acylase is reported. The immobilisation is efficient and the enzymatic preparation shows high specific activity and thermal stability. The technique opens new perspectives for the preparation of innovative tailor-made supports matching specific requirements of enzymatic processes.
Keywords:biocatalysis  covalent immobilisation  penicillin G acylase  organically modified silicates  xerogel
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