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Palladium-catalyzed stereoselective synthesis of 3-(aminomethylene)-oxindoles |
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| Authors: | Morteza BararjanianSaeedeh Hosseinzadeh Saeed Balalaie Hamid Reza BijanzadehEckardt Wolf |
| Institution: | a Peptide Chemistry Research Center, K.N. Toosi University of Technology, PO Box 15875-4416, Tehran, Iran b Department of Chemistry, Tarbiat Modares University, PO Box 141115-175, Tehran, Iran c Tofigh Daru Res. & Eng. Co., 61st St. km 18 Karaj Highway, Tehran 37515-375, Iran |
| Abstract: | An efficient palladium-catalyzed protocol for the stereoselective synthesis of 3-(aminoarylmethylene)-oxindoles has been developed. In this approach, Ugi-4-component reaction adducts were used as starting materials for carbopalladative cyclization-Buchwald reaction sequences. |
| Keywords: | Carbopalladative cyclization Buchwald reaction 3-(Aminoarylmethylene)-oxindoles Active acetylenic compounds Stereoselective synthesis |
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