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Antimicrobial activities of single aroma compounds
Authors:Schmidt Erich  Bail Stefanie  Friedl Susanne Mirjam  Jirovetz Leopold  Buchbauer Gerhard  Wanner Jürgen  Denkova Zapryana  Slavchev Alexander  Stoyanova Albena  Geissler Margit
Institution:Gottfried Keller Strasse 8, D-86720 N?rdlingen, Germany. info@artandfragrance.de
Abstract:Commercially available aroma samples were evaluated for their olfactory quality by professional perfumers and tested for their antimicrobial activity. Agar diffusion and agar-dilution were used as test methods and a set of two Gram-positive (Staphylococcus aureus and Enterococcus faecalis) and four Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris G, Klebsiella pneumoniae and Salmonella abony) and a yeast, Candida albicans, were the test microorganisms. All the investigated compounds were active against Gram-positive bacteria, especially beta-caryophyllene against Enterococcus faecalis (MIC 6 ppm), but only few substances showed activity towards Gram-negative bacteria, except for cinnamic acid, which was active against all (MIC 60 ppm) and Candida albicans, against which cinnamic acid and caryophyllene oxide showed high activity (MIC < 60 ppm).
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