Recent trends in the synthesis of 1,2,3-thiadiazoles |
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| Authors: | Ali Irfan Fozia Batool Sajjad Ahmad Riaz Ullah Aeysha Sultan Rabia Sattar |
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| Affiliation: | 1. Department of Chemistry, The University of Lahore, Sargodha, Pakistan;2. aliirfanrai@hotmail.com;4. Department of Chemistry, UET Lahore, Faisalabad, Pakistan;5. Medicinal Aromatic and Poisonous Plants Research Center, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;6. Department of Chemistry, University of Education, Faisalabad, Pakistan |
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| Abstract: | ![]()
Abstract1,2,3-Thiadiazoles, structurally active pharmacophores have attracted significant attention of synthetic chemists, medicinal and pharmaceutical researchers because of their versatile biological activities against various diseases such as herbicidal, insecticidal, antiviral, antitumor, antimicrobial, anticancer, plants activator and anti-amoebic activities. A literature survey of the last decade presented in this review article summarizes the major synthetic approaches, methodologies and strategies adopted for the synthesis of 1,2,3-thiadiazole scaffolds which will be help for medicinal chemists and pharmacists in future synthesis and development of novel therapeutic agents. |
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| Keywords: | 1,2,3-Thiadiazole derivatives one-pot-synthesis cyclization triazole pyrazole |
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