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Efficient α-Thiocyanation of Ketones Using Pyridinium Hydrobromide Perbromide |
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| Authors: | Liqiang Wu Xiaojuan Yang |
| Institution: | 1. School of Pharmacy , Xinxiang Medical University , Xinxiang , Henan , China;2. College of Chemistry and Chemical Engineering , Xinxiang University , Xinxiang , Henan , China |
| Abstract: | Abstract The direct α-thiocyanation of ketones with ammonium thiocyanate has been achieved using pyridinium hydrobromide perbromide under mild and neutral conditions to produce α-ketothiocyanates in excellent yields and with high selectivity. |
| Keywords: | Thiocyanation ketones ammonium thiocyanate pyridinium hydrobromide perbromide synthesis |