Phosphorylated Allylchlorides: A Source of new Structures and Transformations |
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| Authors: | Yu. G. Gololobov A. S. Oganesyan G.D. Kolominikova S. A. Kuznetsova |
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| Affiliation: | A.N. Nesmeyanov Institute of Organoelement Compounds, Academy of Sciences of the USSR , Vavilova Str. 28, Moscow, 117334, USSR |
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| Abstract: | Abstract General methods have been elaborated for the synthesis of O (or S)-phosphorylated vinylcholines, including the corresponding betaines of mono-, bis- and polymer structures, 5-membered heterocycles with P, O, S, N atoms in the cycle and exo- CHX= (X=H, C1) bond. The key substances, O-phos- phorylated allylchlorides, were obtained either by the well known Perkov reaction or according to scheme (I), worked out by us. The scheme is based on the reactions of 3- or 4-coordinated phosphorus with substituted ketones in the presence of triethylamine (B:). |
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| Keywords: | Structure-taste sulfamate sweetener QSAR. |
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