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Phosphate-Phosphonate Rearrangement of Aliphatic Phosphates |
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| Authors: | Susanne Schmidt Friedrich Hammerschmidt |
| Affiliation: | Department of Organic Chemistry , University of Vienna , A-1090 , Vienna , Austria |
| Abstract: | Abstract Phosphorylation of various aliphatic alcohols gives phosphates 1 which are deprotonated by sBuLi/TMEDA in diethyl ether, THF or hexane at ?78 °C. The organo-lithiurns 2 and 4 formed isornerize to α-hydroxy- phosphonates 3 and 5 (phosphate-phosphonate rearrangement[1.2] |
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