ACTIVATED NITRILES IN HETEROCYCLIC SYNTHESIS: NOVEL SYNTHESIS OF PYRROLO[1,2-c]IMIDAZOLE AND PYRANO[2,3-d]IMIDAZOLE DERIVATIVES |
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| Authors: | Mahfouz A. Abdelaziz H. H. Moharram Samy A. Essawy A. A. Mohamed |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science , Cairo University;2. National Organisation for Drug Control and Research , Egypt;3. Department of Chemistry, Faculty of Science , Banha University |
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| Abstract: | Abstract Several new pyrrolo[1,2-ylidene ethyl cyanoacetate (lc, d) with each of (2) and (11) afforded the 5-ylidene-2-thiohydantoins (Sa, b), (Wn. b) respectively. Compounds Sn, b react with each of malononitrile and ethyl cyanoacet-ate to give the corresponding pyrroloimidazole derivatives (h,b) and (an, b) respectively. The structure of the isolated products were established by elemental analyse and spectral data studies. |
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| Keywords: | Arylthioacetates arylthiopropionates NMR- and mass spectra |
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