NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions |
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| Authors: | Chun-Wei Kuo |
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| Affiliation: | Department of Chemistry, National Taiwan Normal University, 88, Sec. 4, Tingchow Road, Taipei 116, Taiwan, ROC |
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| Abstract: | Various biologically important 1,5-benzodiazepine derivatives were efficiently synthesized in excellent yields using catalytic amounts of NBS (10 mol %). This inexpensive, nontoxic, and readily available catalyst efficiently catalyzes the condensation of several aromatic as well as aliphatic ketones with substituted o-phenylenediamines. |
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