Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
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| Authors: | Ignazio Blanco,Alberta Latteri,Gianluca Cicala,Antonio D’ Angelo,Veronica Viola,Vincenzo Arconati,Michelina Catauro |
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| Affiliation: | 1.Department of Civil Engineering and Architecture and INSTM UdR, University of Catania, V.le A. Doria 6, 95125 Catania, Italy; (I.B.); (A.L.); (G.C.);2.Department of Engineering, University of Campania “Luigi Vanvitelli”, Via Roma 29, 81031 Aversa, Italy; (A.D.); (V.V.); (V.A.);3.Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania “Luigi Vanvitelli”, Via Vivaldi 43, 81100 Caserta, Italy |
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| Abstract: | ![]()
This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus). |
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| Keywords: | sol– gel method, hybrids materials, anti-bacterial properties, FT-IR, SEM |
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