| 盐酸曲马多药物树脂制备技术的研究 |
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| 引用本文： | 张志燕,平其能.盐酸曲马多药物树脂制备技术的研究[J].离子交换与吸附,1999,15(4):289-296. |
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| 作者姓名： | 张志燕 平其能 |
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| 作者单位： | 中国药科大学药剂教研究!南京２１０００９ |
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| 摘 要： | 采用静态法和动态法和工艺制备盐酸曲马多药物树脂，并对制备过程中体系温度，反应时间，药物溶液浓度，溶液流速等影响因素进行了研究；以正交设计对工艺进行优化。
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| 关 键 词： | 盐酸曲马多 药物树脂 药物控释材料 |
STUDIES ON THE PREPARATION TECHNOLOGY OF TRAMADOL-RESIN COMPLEXES |
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| Zhang Zhiyan, Ping Qineng.STUDIES ON THE PREPARATION TECHNOLOGY OF TRAMADOL-RESIN COMPLEXES[J].Ion Exchange and Adsorption,1999,15(4):289-296. |
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| Authors: | Zhang Zhiyan Ping Qineng |
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| Abstract: | Tramadol-resin complexes were prepared by batch and column process. Parameters thatinfluence the processing, such as operating temperature, reaction duration, initial drug concentration, velocity of floW, were stUdied. Factorial design was utilized to optimize the process. |
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| Keywords: | Tramadol HCI Resinate BatCh method Column method Influence Parameters Factorial design |
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