| 苯佐卡因高分子载体药物及其纳米微球的合成 |
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| 引用本文： | 孙玉,沈良骏.苯佐卡因高分子载体药物及其纳米微球的合成[J].合成化学,2007,15(3):382-384. |
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| 作者姓名： | 孙玉 沈良骏 |
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| 作者单位： | 1. 江苏大学,药学院,江苏,镇江,212013
2. 安徽师范大学,化学与材料科学学院,安徽,芜湖,241000 |
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| 摘 要： | 将苯佐卡因通过酯键和甲基丙烯酸相连,合成了含苯佐卡因的可聚合单体(BM),BM自聚得到苯佐卡因高分子载体药物(PBM),并采用乳液聚合法制备了PBM纳米微球。PBM的结构经1H NMR和TEM表征。
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| 关 键 词： | 苯佐卡因 高分子载体药物 纳米微球 合成 |
| 文章编号： | 1005-1511（2007）03-0382-03 |
| 收稿时间： | 2006-11-03 |
| 修稿时间： | 2006年11月3日 |
Synthesis of Polymeric Carrier Drug and Its Nano-microspheres |
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| SUN Yu,SHEN Liang-jun.Synthesis of Polymeric Carrier Drug and Its Nano-microspheres[J].Chinese Journal of Synthetic Chemistry,2007,15(3):382-384. |
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| Authors: | SUN Yu SHEN Liang-jun |
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| Institution: | 1. School of Pharmacy, Jiangsu University, Zhenjiang 212013, China; College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China |
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| Abstract: | Polymeric carrier drug(PBM) was synthesized by self-polymerization of BM,a unsaturated monomers prepared by attaching benzocaine to methacrylic acid through covalent linkage.The nano-microspheres of PBM were prepared by emulsion polymerization from BM.The structure of PBM was characterized by 1H NMR and TEM. |
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| Keywords: | benzocaine polymeric carrier drug nano-microspheres synthesis |
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