Organocatalytic Formal Intramolecular [3+2]-Cycloaddition to Acquire Biologically Important Methanodibenzo[a,f]azulenes and Methanobenzo[f]azulenes |
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| Authors: | Dr Swamy Peraka Mohammed Anif Pasha Dr Guguloth Thirupathi Prof Dr Dhevalapally B Ramachary |
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| Institution: | Catalysis Laboratory, School of Chemistry, University of Hyderabad, Hyderabad, 500 046 India |
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| Abstract: | Lawsones were transformed into the functionally rich framework of methanodibenzoa,f]azulenes and methanobenzof]azulenes in a single- or two-pot operation through five organocatalytic sequential reactions in very good yields with excellent selectivities. These resultant molecules are basic skeletons of important antibiotics, which highlights the value of this formal intramolecular 3+2]-cycloaddition as a key protocol. |
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| Keywords: | [3+2]-cycloaddition Knoevenagel condensation lawsones methanobenzo[f]azulenes organocatalysis |
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