Synthesis of a 4′,4′-spirothietane-2′, N-cycloadenosine as a highly constrained analogue of 5′-deoxy-5′-methylthioadenosine (MTA) |
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| Authors: | Gustavo S.G. De Carvalho Robert H. Dodd |
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| Affiliation: | a Departamento de Quimica, ICE, Universidade Federal de Juiz de Fora 36036-900, Juiz de Fora, MG, Brazil
b Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, France |
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| Abstract: | The synthesis of the highly constrained adenosine derivative 7 featuring at spirothietane at C-4′, which may be considered as a rigid analogue of MTA, is described. |
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