Multicomponent reactions for the synthesis of new 3′-indolyl substituted heterocycles under microwave irradiation |
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| Authors: | Song-Lei Zhu Shun-Jun Ji Kai Zhao |
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| Affiliation: | a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou(Soochow) University, Suzhou 215123, People’s Republic of China
b Department of Chemistry, Xuzhou Medical College, Xuzhou 221002, People’s Republic of China |
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| Abstract: | A series of polysubstituted (3′-indolyl)pyrazolo[3,4-b]pyridine and (3′-indolyl)benzo[h]quinoline derivatives were synthesized via one-pot multicomponent reactions of aldehydes, 3-cyanoacetyl indoles with 5-aminopyrazol or naphthylamine under microwave irradiation. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure. |
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| Keywords: | Indole Heterocycle Multicomponent reactions Microwave irradiation |
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