A novel and facile synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones via a one-pot multi-component reaction |
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Authors: | Majid M. Heravi Bita Baghernejad Hossein A. Oskooie Rahim. Hekmatshoar |
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Affiliation: | Department of Chemistry, School of Science, Azzahra University, Vanak, Tehran, Iran |
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Abstract: | A simple and efficient synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones was achieved via a one-pot multi-component reaction of cyclohexyl isocyanide, an aldehyde, a 1,3-dicarbonyl compound, and ammonium acetate in the presence of a catalytic amount of KHSO4 in acetonitrile. |
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Keywords: | Cyclohexyl isocyanide 1,3-Dicarbonyl compound Multi-component reaction 1H-Indole-4(5H)-ones |
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