A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414) |
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| Authors: | Emmanuel Pinard,Serge Burner,Franç ois Montavon |
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| Affiliation: | a F. Hoffmann-La Roche Ltd, Pharmaceutical Research Basel, Discovery Chemistry, CH-4070 Basel, Switzerland
b F. Hoffmann-La Roche Ltd, Pharmaceutical Research Basel, Chemical Synthesis, CH-4070 Basel, Switzerland |
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| Abstract: | A short and efficient synthesis of the NMDA glycine site antagonist: (3R,4R)-3-amino-1-hydroxy-4-methyl pyrrolidin-2-one (L-687,414) is described. |
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