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Acetylene black nanoparticle-modified electrode as an electrochemical sensor for rapid determination of rutin
Authors:Jinchun Song  Ji Yang  Junfen Zeng  Juan Tan  Li Zhang
Affiliation:1. Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, 430060, People’s Republic of China
2. College of Pharmacy, Wuhan University, Wuhan, 430077, People’s Republic of China
Abstract:Acetylene black nanoparticles were homogeneously dispersed into water in the presence of hydrophobic surfactant and then used to modify the surface of a glassy carbon electrode. An examination of the electrochemistry of rutin showed that this modification of the electrodes resulted in a considerable enhancement of the surface, thus remarkably increasing the signal for rutin. As a result, a sensitive and convenient electrochemical method was developed for the determination of rutin. The linear range is from 20 μg L-1 to 5 mg L-1, and the limit of detection is 10 μg L-1. The method was successfully employed to the determination of rutin in traditional Chinese medicines.
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