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Monte Carlo Simulation of Kinesin Movement with a Lattice Model
作者姓名:王宏  窦硕星  王鹏业
作者单位:Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080
基金项目:Supported by the National Natural Science Foundation of China under Grant Nos 60025516 and 10334100.
摘    要:

关 键 词:格子模型  Kinesin运动  ATP分子  Monte  Carlo模拟  分子动力
收稿时间:2005-06-30
修稿时间:2005-06-30

Monte Carlo Simulation of Kinesin Movement with a Lattice Model
WANG Hong, DOU Shuo-Xing, WANG Peng-Ye.Monte Carlo Simulation of Kinesin Movement with a Lattice Model[J].Chinese Physics Letters,2005,22(11):2980-2982.
Authors:WANG Hong  DOU Shuo-Xing  WANG Peng-Ye
Abstract:Kinesin is a processive double-headed molecular motor that moves along a microtubule by taking about 8nm steps. It generally hydrolyzes one ATP molecule for taking each forward step. The processive movement of the kinesin molecular motors is numerically simulated with a lattice model. The motors are considered as Brownian particles and the ATPase processes of both heads are taken into account. The Monte Carlo simulation results agree well with recent experimental observations, especially on the relation of velocity versus ATP and ADP concentrations.
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