Nortriterpene constituents from Schisandra sphenanthera |
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| Authors: | Fei He Xing-Yao Li Guang-Yu Yang Xiao-Nian Li Xiao Luo Juan Zou Yan Li Wei-Lie Xiao Han-Dong Sun |
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| Institution: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China;2. Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, PR China |
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| Abstract: | Nine new highly oxygenated nortriterpenoids, pre-schisanartanins E–J (1–6) and sphenadilactones D–F (7–9), together with 17 known ones (10–26), have been isolated from the acetone extract of the roots and stems of Schisandra sphenanthera. The structures of the new metabolites were characterized on the basis of extensive spectroscopic analyses including 1D and 2D NMR experiments. These compounds were all evaluated for their cytotoxicity against HL-60, SMMC-7721, A549, MCF-7, and SW480 tumor cell lines. |
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