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Studies on the biosynthesis of cholesterol—7 Rearrangement of methyl groups during enzymic cyclisation of squalene
Authors:J W Cornforth  R H Cornforth and A Pelter

M G Horning and G Popj  k

Institution:

National Institute for Medical Research, London UK

M.R.C. Experimental Radiopathology Research Unit, Hammersmith Hospital, London UK

Abstract:The present state of knowledge of the biosynthesis of cholesterol is summarised. An experiment is described wherein a special application of the carbon isotope 13C permits a decision between possible modes of rearrangement during the enzymic cyclisation of squalene.
Keywords:
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