Supramolecular assemblies based on amphiphilic cyclodextrins |
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| Authors: | Anthony W. Coleman Athena Kasselouri |
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| Affiliation: | CNRS, Centre Pharmaceutique, Université de Paris-Sud , Chatenay-Malabry, 92296, France |
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| Abstract: | Abstract The capacity of two types of amphiphilic β-cyclodextrin (CD) derivatives, heptakis-C6-alkylamido β-CD (I) and heptakis-C6-ammonium tetradecakis-O2,O3-alkyl β-CD (II), to form organized assemblies with l α-phosphatidylcholine-dipalmitoyl (dppc) and iotacarrageenan is described. These systems are studied using a Langmuir balance. The formation of stable mixed layers between I and II and dppc is observed. The interaction between II and iota-carrageenan leads to a dimunition in the fluidity of monomolecular layers. The physicochemical properties of I are described via variable temperature 1H-NMR studies. |
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