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A lazy learning-based QSAR classification study for screening potential histone deacetylase 8 (HDAC8) inhibitors
Authors:GP Cao  M Arooj  S Thangapandian  C Park  V Arulalapperumal  Y Kim
Institution:1. Department of Biochemistry, Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Centre (SSAC), Plant Molecular Biology and Biotechnology Research Centre (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University, Jinju, Republic of Korea;2. CHIRI Biosciences Research Precinct, School of Biomedical Sciences, Curtin University, Perth, Australia;3. Department of Science Education, Kyungnam University, Masan, Republic of Korea
Abstract:
Keywords:histone deacetylases 8  K nearest neighbours  neighbourhood classifier  molecular docking  MD simulation  virtual screening
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