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Quantitative structure-activity relationships for cycloguanil analogs as PfDHFR inhibitors using mathematical molecular descriptors |
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| Authors: | S.C. Basak D. Mills |
| Affiliation: | 1. Center for Water and the Environment, Natural Resources Research Institute, University of Minnesota Duluth , Duluth, USA sbasak@nrri.umn.edu;3. Center for Water and the Environment, Natural Resources Research Institute, University of Minnesota Duluth , Duluth, USA |
| Abstract: | |
| Keywords: | cycloguanil analogues dihydrofolate reductase (DHFR) inhibitors Plasmodium falciparum (Pf) ridge regression high-dimensional pharmacophore differential QSARs |