| Abstract: | Gossypol forms various complexes with the isomeric dioxanes. The clathrate with 1,4-dioxane is the only complex of gossypol in which the intrinsic symmetry of the gossypol molecule — the symmetry of a twofold axis — is retained. In this complex, two out of the three 1,4-dioxane molecules belonging to each gossypol molecule participate in the construction of a mixed H-bound gossypol -dioxane matrix, while the third molecule plays the part of guest, the guest molecules having no H-bonds with the host matrix and undergoing desolvation at 108–110°C. |
