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Cetyltrimethylammonium chloride (CTAC) catalyzed one-pot synthesis of novel coumarin-4H-pyran conjugates in aqueous media
Authors:Adil Omar  Keyume Ablajan  Mawjvda Hamdulla
Affiliation:Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China
Abstract:Novel fluorescent coumarin-4H-pyran conjugates were achieved by three-component reactions of various synthetic β-ketoesters with aldehydes and malononitrile in aqueous media. Besides mild reaction conditions, operational simplicity, absence of tedious separation procedures, using of inexpensive and nontoxic commercially available cationic surfactant cetyltrimethylammonium chloride (CTAC) as a catalyst are the prominent advantage of this method.
Keywords:Coumarin  4H-Pyran  Multicomponent reaction  CTAC  Aqueous media  Surfactant catalyzed  
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