Recent catalytic syntheses of trifluoromethylthio-containing organic compounds by transition metals,chiral organocatalysts,and photocatalysts

This review summarizes the recent advances in the catalytic syntheses of CF₃S-containing organic molecules using various nucleophilic or electrophilic trifluoromethylthiolating reagents.C-halogen and C-H bonds in various molecules have been transformed to C-SCF₃ bonds by transition-metal-catalyzed reactions,such as cross-coupling of aryl halides.Enantioselective reactions controlled by chiral metal complexes or chiral organocatalysts have afforded many trifluoromethylthiolated chiral architectures, such as β-ketoesters and oxindoles.Very recently,visible-light-induced photoredox trifluoromethylth-iolations have been developed,providing versatile CF₃S-containing structures efficiently.