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高效液相色谱法测定盐酸羟甲唑啉滴鼻剂的稳定性
引用本文:李太平,宋玉荣. 高效液相色谱法测定盐酸羟甲唑啉滴鼻剂的稳定性[J]. 色谱, 1994, 12(4): 304-304
作者姓名:李太平  宋玉荣
作者单位:丹东市药检所,丹东市中药厂
摘    要:
The stability of oxymetazoline hydrochloride nasal solution was determined by HPLC and the initialaverage rate method. The procedure was carripd out on a 250mm×4. 6mm column with 5μm ODS using wa-ter-methanol-sodium acetate solution(lmol/L)-glacil acetic acid-triethylamine as mobile phase,with UV de-tection at 280nm. The elution was performed at the flow rate of lmL/min. The results show that the expirydate of this preparation is about three years at room temperature.

关 键 词:初均速法.  高效液相色谱  稳定性  盐酸羟甲唑啉滴鼻剂  

Determinaiton of the Stability of Oxymetazoline Hydrochloride Nasal Solution by High Performance Liquid Chromatography(HPLC)
Li Taiping, Song Yurong. Determinaiton of the Stability of Oxymetazoline Hydrochloride Nasal Solution by High Performance Liquid Chromatography(HPLC)[J]. Chinese journal of chromatography, 1994, 12(4): 304-304
Authors:Li Taiping   Song Yurong
Abstract:
Keywords:high performance liquid chromatography   stability oxymetazoline hydrochloride nasal solu-tion  the initial average rate method  
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