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Four New Nortriterpenoids from Schisandra lancifolia
Authors:Wei‐Lie Xiao  Ying‐Li Wu  Shan‐Zhai Shang  Fei He  Xiao Luo  Guang‐Yu Yang  Jian‐Xin Pu  Guo‐Qiang Chen  Han‐Dong Sun
Abstract:Four new highly oxygenated nortriterpenoids, lancifodilactones O–R ( 1 – 4 ), together with six known ones, i.e., 5 – 10 , were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments and mass spectrometry. Compounds 1 – 3 were evaluated for their cytotoxicity against NB4, A549, SHSY5Y, PC‐3, and MCF‐7 cell lines. No compounds exhibited significant cytotoxicity, the IC50 values being above 50 μM .
Keywords:Schisandra lancifolia  Nortriterpenoids  Lancifodilactones O       R
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