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1.
Pattern transition and regulation in a subthalamopallidal network under electromagnetic effect 下载免费PDF全文
Although the significant roles of magnetic induction and electromagnetic radiation in the neural system have been widely studied, their influence on Parkinson's disease (PD) has yet to be well explored. By virtue of the magnetic flux variable, this paper studies the transition of firing patterns induced by magnetic induction and the regulation effect of external magnetic radiation on the firing activities of the subthalamopallidal network in basal ganglia. We find: (i) The network reproduces five typical waveforms corresponding to the severity of symptoms: weak cluster, episodic, continuous cluster, episodic, and continuous wave. (ii) Magnetic induction is a double-edged sword for the treatment of PD. Although the increase of magnetic coefficient may lead the physiological firing activity to transfer to pathological firing activity, it also can regulate the pathological intensity firing activity with excessive β-band power transferring to the physiological firing pattern with weak β-band power. (iii) External magnetic radiation could inhibit continuous tremulous firing and β-band power of subthalamic nucleus (STN), which means the severity of symptoms weakened. Especially, the bi-parameter plane of the regulation region shows that a short pulse period of magnetic radiation and a medium level of pulse percentage can well regulate pathological oscillation. This work helps to understand the firing activity of the subthalamopallidal network under electromagnetic effect. It may also provide insights into the mechanisms behind the electromagnetic therapy of PD-related firing activity. 相似文献
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窄禁带直接带隙半导体材料碲镉汞(Hg1–xCdxTe)是一种在红外探测与自旋轨道耦合效应基础研究方面都具有重要应用意义的材料.本文对单晶生长的体材料Hg0.851Cd0.149Te进行阳极氧化以形成表面反型层,将样品粘贴在压电陶瓷上减薄后进行磁输运测试,在压电陶瓷未加电压时观察到了明显的SdH振荡效应.对填充因子与磁场倒数进行线性拟合,获得样品反型层二维电子气的载流子浓度为ns=1.25×10^16m^-2.在不同磁场下,利用压电陶瓷对样品进行应力调控,观测到具有不同特征的现象,分析应是样品中存在二维电子气与体材料两个导电通道.零磁场下体材料主导的电阻的变化应来源于应力导致的带隙的改变;而高场下产生类振荡现象的原因应为应力导致的二维电子气能级的分裂. 相似文献
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The present work is an experimental study of two oscillating rigid plates placed in side-by-side configuration, hinged at their leading edges, subjected to low subsonic flow. This problem is investigated using smoke-wire flow visualization, hot-wire anemometry, and time resolved particle image velocimetry. It is found that beyond a critical Reynolds number, the plates set into oscillatory motion. This critical Reynolds number depends on the gap between the plates. It is also seen that this value of Reynolds number, at lower values of gap to thickness ratio (<7) is significantly higher than that of the single plate configuration value. The frequency and amplitude of the oscillating plates at various gaps and Reynolds numbers have been studied and compared with the characteristics of an oscillating single plate. It is also found that depending on the gap and acceleration of the free-stream, there exist two modes of oscillation - (i) in-phase and (ii) out-of-phase. For gap to thickness ratio less than 10, only in-phase oscillations take place for all values of free-stream velocity considered in the present work, whereas, when this ratio is greater than 10, the mode of oscillation depends on the initial conditions up to a certain free-stream velocity, beyond which the plates switch to in-phase mode. Smoke wire flow visualization technique along with time resolved particle image velocimetry reveal that the vorticity distributions around the plates are responsible for the initiation of the two modes of oscillations. 相似文献
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Nonlinear effects such as friction and freeplay on the control surfaces can affect aeroelastic dynamics during flight. In particular, these nonlinearities can induce limit cycle oscillations (LCO), changing the system stability, and because of this it is essential to employ computational methods to predict this type of motion during the aircraft development cycle. In this context, the present article presents a matrix notation for describing the Hénon’s method used to reduce errors when considering piecewise linear nonlinearities in the numerical integration process. In addition, a new coordinate system is used to write the aeroelastic system of equations. The proposal defines a displacement vector with generalized and physical variables to simplify the computational implementation of the Hénon’s technique. Additionally, the article discusses the influence of asymmetric freeplay and friction on the LCO of an airfoil with control surface. The results show that the extended Hénon’s technique provides more accurate LCO predictions, that friction can change the frequency and amplitude of these motions, and the asymmetry of freeplay is important to determine the LCO behavior. 相似文献
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通过引入子电路模块, 并选取适当的参数及非线性电阻特性, 建立了多时间尺度下具有多平衡态的四维广义哈特利(Hartley) 电路模型. 基于快子系统的多平衡态及其稳定性, 给出了参数空间的分岔集, 得到了不同区域中的动力学特性及其相应的分岔模式和临界条件. 针对两种典型具有不同分岔特征的情形, 分别给出了多平衡态参与下的两种不同的周期簇发振荡行为, 结合快子系统的分岔分析, 揭示了沉寂态和激发态之间相互转化的产生机制, 指出多平衡态不仅会导致多种沉寂态和激发态同时参与同一周期簇发振荡, 也会导致簇发振荡模式的多样性. 相似文献
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In this paper, hydrodynamic force coefficients and wake vortex structures of uniform flow over a transversely oscillating circular cylinder beneath a free surface were numerically investigated by an adaptive Cartesian cut-cell/level-set method. At a fixed Reynolds number, 100, a series of simulations covering three Froude numbers, two submergence depths, and three oscillation amplitudes were performed over a wide range of oscillation frequency. Results show that, for a deeply submerged cylinder with sufficiently large oscillation amplitudes, both the lift amplitude jump and the lift phase sharp drop exist, not accompanied by significant changes of vortex shedding timing. The near-cylinder vortex structure changes when the lift amplitude jump occurs. For a cylinder oscillating beneath a free surface, larger oscillation amplitude or submergence depth causes higher time-averaged drag for frequency ratio (=oscillation frequency/natural vortex shedding frequency) greater than 1.25. All near-free-surface cases exhibit negative time-averaged lift the magnitude of which increases with decreasing submergence depth. In contrast to a deeply submerged cylinder, occurrences of beating in the temporal variation of lift are fewer for a cylinder oscillating beneath a free surface, especially for small submergence depth. For the highest Froude number investigated, the lift frequency is locked to the cylinder oscillation frequency for frequency ratios higher than one. The vortex shedding mode tends to be double-row for deep and single-row for shallow submergence. Proximity to the free surface would change or destroy the near-cylinder vortex structure characteristic of deep-submergence cases. The lift amplitude jump is smoother for smaller submergence depth. Similar to deep-submergence cases, the vortex shedding frequency is not necessarily the same as the primary-mode frequency of the lift coefficient. The frequency of the induced free surface wave is exactly the cylinder oscillation frequency. The trends of wave length variation with the Froude number and frequency ratio agree with those predicted by the linear theory of small-amplitude free surface waves. 相似文献
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Basak Karpuz 《Mathematical Methods in the Applied Sciences》2019,42(9):2993-3001
In this paper, we give new sufficient conditions for both oscillation and nonoscillation of the delay dynamic equation where and satisfy τ(t) ≤ σ(t) for all large t and . As an important corollary, we obtain the time scale invariant integral condition for nonoscillation: for all large t. Also, with some examples, we show that newly presented results are sharp. 相似文献