Synthesis of pyrazolo[1,5-a]-pyrimidines by reaction of 3,5-diamino-4-nitropyrazole with acetoacetic ester in the presence of alkaline agents

Two major compounds are formed in the reaction of 3,5-diamino-4-nitropyrazole with acetoacetic ester: 2-amino-5-methyl-3-nitro-4,7-dihydropyrazolo[1,5-a]pyrimidin-7-one and 3-amino-5-(-hydroxycrotonyl)amino-4-nitropyrazole. The latter is converted to bicyclic dihydropyrazolo[1,5-a]-pyrimidinone in solutions with heating.State Science Center of the Russian Federation NIOPIK (Scientific Research Institute of Organic Intermediates and Dyes), Moscow 103787Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 73–77, January, 2000.     

3,4-二硝基吡唑合成方法及性能研究综述

3,4-二硝基吡唑(DNP)是最近报道的,可替代TNT作为熔铸炸药载体的含能化合物.本文以DNP的合成原料为主线综述了其合成方法,分析了各种方法的优劣,提出了较为可行的工艺路线;同时简述了DNP的物理化学性质,并通过与其他含能物质(包括部分熔铸炸药载体)对比,指出DNP作为熔铸炸药载体具有一定的优势.