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1.
Reinhard Oertel Norman Arenz Sten Gunnar Zeitz Jörg Pietsch 《Biomedical chromatography : BMC》2015,29(8):1290-1296
With screening methods in the legal medicine drugs were often detected in autopsy material. In this study the antiarrhythmic and the local anesthetic drug lidocaine could be proved in fifty‐one cases and determined in different autopsy materials. For the first time the comparison of so many distribution patterns of lidocaine in human compartments was possible. A liquid‐liquid extraction procedure, a standard addition method and LC/MS/MS were used for analytics. The measured concentrations in blood were in the therapeutic range or lower. The time between lidocaine application and death was given in twenty‐nine cases. These data were very helpful to estimate and interpret the distribution process of lidocaine between application and death. This time exerted a crucial influence on the distribution of lidocaine in the compartments. Most of the intravenous applicated lidocaine was found in heart blood after a very short time of distribution. Afterwards the highest concentrations were measured in brain. Later the highest concentration was found in the kidney samples or in urine. If the time between lidocaine application and death is known, the results of this study can be used to deepen the knowledge of its pharmacokinetics. If this time is unknown, the circumstances and the causes of death can be better explained. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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V. V. Bolotov V. S. Kovivchak A. A. Korepanov E. V. Knyazev S. N. Nesov V. E. Roslikov Yu. A. Sten’kin P. M. Korusenko R. V. Shelagin 《Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques》2011,5(6):1185-1188
Layers of por-Si/SnO
x
nanocomposite formed by high-power ion beam irradiation with nanosecond duration have been studied. The results of structural
and elemental analyses of these layers are presented. The high sensitivity of this nanocomposite to low NO2 concentrations at room temperature has been revealed. 相似文献
4.
V. V. Alekseenko D. M. Gromushkin Yu. V. Sten’kin 《Bulletin of the Russian Academy of Sciences: Physics》2011,75(6):857-859
Thermal neutron fluxes were measured using two types of scintillation detectors based on the inorganic scintillator ZnS(Ag):
6LiF+ZnS(Ag) and 10B2O3 + KCl+ZnS(Ag). The preliminary results from these measurements are given. The thermal neutron concentration as a function
of altitude above sea level was determined. The measurements were performed at three locations: in Moscow, at the Baksan Neutrino
Observatory of the Russian Academy of Sciences, and at the Gran Sasso National Laboratory. Variations of neutron count rates
associated with lunar cycles were observed at the remote laboratories. 相似文献
5.
V. V. Bolotov N. A. Davletkil’deev A. A. Korotenko V. E. Roslikov Yu. A. Sten’kin 《Technical Physics》2011,56(11):1593-1598
The layer-by-layer distribution of components in a porous silicon-tin oxide nanocomposite produced by the following three
methods is studied by spectroscopic ellipsometry: chemical vapor deposition, atomic layer deposition, and magnetron sputtering.
It is shown that, in the nanocomposites fabricated by these methods, SnO
x
penetrates to a depth more than 400 nm and is nonuniformly distributed over the porous layer thickness. The nanocomposite
prepared by magnetron sputtering followed by heat treatment has the maximum penetration depth and the maximum uniformity of
layer-by-layer SnO
x
distribution. 相似文献
6.
Sten Scheibye Bjarne S. Pedersen S.-O. Lawesson 《Phosphorus, sulfur, and silicon and the related elements》2013,188(1-2):271-272
Abstract Recent studies have shown that the dimer of p-methoxyphenylthionophosphinesulfide, 1, is a very superior thiation reagent, as ketones, amides, and esters are in most cases quantitatively converted to their thio-analogues. 相似文献
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