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Previous studies suggesting that people predict chaotic sequences better than chance have not discriminated between sensitivity to nonlinear determinism and facilitation using autocorrelation. Since prediction accuracy declines with increases in the look-ahead window in both cases, a decline in prediction accuracy does not imply chaos sensitivity. To overcome this problem, phase-randomized surrogate time series are used as a control. Such series have the same linear properties as the original chaotic sequence but contain no nonlinear determinism, i.e. chaos. In the experimental task, using a chaotic Hénon attractor, participants viewed the previous eight days temperatures and then predicted temperatures for the next four days, over 120 trials. The control group experienced a sample from a corresponding phase-randomized surrogate series. Both time series were linearly transformed to provide a realistic temperature range. A transformation of the correlation between observed and predicted values decreased over days for the chaotic time series, but remained constant and high for the surrogate series. The interaction between the days and series factors was statistically significant, suggesting that people are sensitive to chaos, even when the autocorrelation functions and power spectra of the control and experimental series are identical. Implications for the psychological assessment of individual differences in human prediction are discussed. 相似文献
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Audra M. Judd Danielle B. Gutierrez Jessica L. Moore Nathan Heath Patterson Junhai Yang Carrie E. Romer Jeremy L. Norris Richard M. Caprioli 《Journal of mass spectrometry : JMS》2019,54(8):ii-ii
Matrix‐assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a molecular imaging technology uniquely capable of untargeted measurement of proteins, lipids, and metabolites while retaining spatial information about their location in situ. This powerful combination of capabilities has the potential to bring a wealth of knowledge to the field of molecular histology. Translation of this innovative research tool into clinical laboratories requires the development of reliable sample preparation protocols for the analysis of proteins from formalin‐fixed paraffin‐embedded (FFPE) tissues, the standard preservation process in clinical pathology. Although ideal for stained tissue analysis by microscopy, the FFPE process cross‐links, disrupts, or can remove proteins from the tissue, making analysis of the protein content challenging. To date, reported approaches differ widely in process and efficacy. This tutorial presents a strategy derived from systematic testing and optimization of key parameters, for reproducible in situ tryptic digestion of proteins in FFPE tissue and subsequent MALDI IMS analysis. The approach describes a generalized method for FFPE tissues originating from virtually any source. 相似文献
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