全文获取类型
收费全文 | 516篇 |
免费 | 19篇 |
国内免费 | 4篇 |
专业分类
化学 | 319篇 |
晶体学 | 2篇 |
力学 | 11篇 |
数学 | 127篇 |
物理学 | 80篇 |
出版年
2023年 | 2篇 |
2022年 | 3篇 |
2021年 | 8篇 |
2020年 | 11篇 |
2019年 | 11篇 |
2018年 | 3篇 |
2017年 | 3篇 |
2016年 | 12篇 |
2015年 | 14篇 |
2014年 | 12篇 |
2013年 | 25篇 |
2012年 | 38篇 |
2011年 | 30篇 |
2010年 | 22篇 |
2009年 | 14篇 |
2008年 | 26篇 |
2007年 | 35篇 |
2006年 | 28篇 |
2005年 | 21篇 |
2004年 | 29篇 |
2003年 | 15篇 |
2002年 | 11篇 |
2001年 | 7篇 |
2000年 | 8篇 |
1999年 | 2篇 |
1998年 | 5篇 |
1997年 | 7篇 |
1996年 | 4篇 |
1995年 | 4篇 |
1994年 | 12篇 |
1993年 | 8篇 |
1992年 | 15篇 |
1991年 | 12篇 |
1990年 | 6篇 |
1989年 | 15篇 |
1988年 | 7篇 |
1987年 | 2篇 |
1986年 | 4篇 |
1985年 | 6篇 |
1984年 | 7篇 |
1983年 | 4篇 |
1982年 | 4篇 |
1981年 | 6篇 |
1980年 | 3篇 |
1978年 | 5篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1967年 | 1篇 |
排序方式: 共有539条查询结果,搜索用时 31 毫秒
1.
It is shown that for , there exists an optimal packing with triples on points that contains no Pasch configurations. Furthermore, for all (mod 6), there exists a pairwise balanced design of order , whose blocks are all triples apart from a single quintuple, and that has no Pasch configurations amongst its triples. 相似文献
2.
Lorraine M. Deck Robert T. Paine Elizabeth R. BrightSabrina Ouizem Diane A. Dickie 《Tetrahedron letters》2014
Simple, aqueous-based syntheses of methylpyridine and methylpyridine N-oxide decorated 3,4-dihydro-2H-naphthoxazine and 2,3-dihydro-1H-naphthoxazine monomers, as well as thermally promoted syntheses of 3,4-dihydro-2H-benzoxazine monomers and bisoxazine methylpyridine derivatives of substituted 1,5-, 2,6-, and 2,7-dihydroxynaphthalenes are described. The crystal structures of two derivatives are presented. 相似文献
3.
Alembert T. Tchinda Simplice R. Mouokeu Rosalie A.N. Ngono Madeleine R.E. Ebelle Aristide L.K. Mokale Diane K. Nono 《Natural product research》2015,29(21):1990-1994
A phytochemical investigation of the whole plant of Crassocephalum bauchiense Huch. resulted in the isolation of a new clerodane diterpenoid, ent-2β,18,19-trihydroxycleroda-3,13-dien-16,15-olide (1), together with two known flavonoids 3′,5-dihydroxy-4′,5′,6,7,8-pentamethoxyflavone (2) and 4′,5-dihydroxy-3′,5′,6,7,8-pentamethoxyflavone (3). The compounds were tested against the chloroquine-sensitive 3D7 strain of Plasmodium falciparum. Compound 2 showed weak activity (IC50 = 10.1 g/mL) whilst compounds 1 and 3 were inactive. The structures of the compounds were elucidated by using detailed spectral analyses, especially 1H and 13C NMR, 1H–1H COSY, NOESY, HMBC and HR-ESI-MS. 相似文献
4.
Xihong Wang Diane V. Michelangeli 《中国颗粒学报》2006,4(6):261-271
Liquid and solid particles in polar stratospheric clouds (PSCs) have been known to play a crucial role in the chemical loss of stratospheric ozone over the Antarctic and Arctic regions in late winter and early spring. The stratospheric aerosol and cloud particles provide the sites where fast heterogeneous chemical reactions convert inactive halogen reservoir species into potential ozone destroying radicals. The sedimentation of nitric acid-containing PSC particles irreversibly removes HNO3 gas (denitrification) from the lower stratosphere, which slows the return of chlorine to its inactive forms, resulting in more severe stratospheric ozone destruction. Although these clouds have been investigated extensively during the past decade using in situ field observation, laboratory experiment and modeling studies, the detailed microphysics processes under cold stratospheric conditions are still uncertain. This paper reviews the recent advances in our understanding of PSCs. 相似文献
5.
Creating scientifically literate students is a common goal among educational stakeholders. An understanding of nature of science is an important component of scientific literacy in K‐12 science education. Q methodology was used to investigate the opinions of preservice and in‐service teachers on how they intend to teach or currently teach science. Q methodology is a measurement tool designed to capture personal beliefs. Participants included 40 preservice and in‐service elementary and secondary science teachers who sorted 40 self‐referential statements regarding science instruction. The results identified three epistemologies toward teaching science: A Changing World, My Beliefs, and Tried and True. Participants with the A Changing World epistemology believe evidence is reliable, scientific knowledge is generated in multiple ways, and science changes in light of new evidence. The My Beliefs epistemology reflects that scientific knowledge is subject to change due to embedded bias, science is affected by culture and religion, and evolution should not be taught in the classroom. The Tried and True epistemology views a scientific method as an exact method to prove science, believes experiments are crucial for scientific discoveries, absolute truth exists in scientific knowledge, and society and cultural factors can be eliminated from investigations. Implications for preservice teacher education programs and in‐service teacher professional development are addressed. 相似文献
6.
7.
For strain sufficiently small such that Hooke's Law is valid, it is shown that only a linear model for axial deformation of rotating rods can be derived. As discussed in the literature, this linear model exhibits an instability when the angular speed reaches a certain critical value. However, unless this linear model is valid for large strain, it is impossible to determine whether this instability really exists; because, as the angular speed is increased, the strain becomes large well short of the critical speed. Next, axial deformation of rotating rods is analyzed using two strain energy functions to model non-linear elastic behavior. The first of these functions is the usual quadratic strain energy function augmented with a cubic term. With this model it is shown that no instability exists if the non-linearity is stiffening (i.e. if the coefficient of the cubic term is positive), although the strain can become large. If the non-linearity is of the softening variety, then the critical angular speed drops as the degree of softening increases. Still, the strains are large enough that, except for rubber-like materials, a non-linear elastic model is not likely to be appropriate. The second strain energy function is based on the square of the logarithmic strain and yields a softening model. It quite accurately models the behavior of certain rubber rods which exhibit the instability within the validated range of elongation. 相似文献
8.
9.
Hadley A. Iliff Diane L. Lynch Evangelia Kotsikorou Patricia H. Reggio 《Journal of computational chemistry》2011,32(10):2119-2126
The cannabinoid CB1 receptor is a class A G protein‐coupled receptor (GPCR) that is the most widely expressed GPCR in the brain. Many GPCRs contain allosteric binding sites for endogenous and/or synthetic ligands, which are topographically distinct from the agonist‐binding site that is known as the orthosteric site. While both endogenous and synthetic ligands that act at the CB1 orthosteric site have been known for some time, compounds that act at a CB1 allosteric site have only recently been discovered. The most studied of these is 5‐chloro‐3‐ethyl‐1H‐indole‐2‐carboxylic acid [2‐(4‐piperidin‐1‐ylphenyl)ethyl]amide (Org27569). Because allosteric ligands are thought to act through conformational changes in the receptor that are transmitted from the allosteric to the orthosteric site, computational studies of the structural and dynamic interactions of Org27569 with the CB1 receptor are crucial to achieve a molecular level understanding of the basis of action of this important new class of compounds. To date, such computational studies have not been possible due to the lack of a complete set of molecular mechanics force field parameters for Org27569. Here, we present the development of missing CHARMM force field parameters for Org27569 using previously published methods and the validation and application of these new parameters using normal mode analysis and molecular dynamics simulations combined with experimental infrared measurements. © 2011 Wiley Periodicals, Inc. J Comput Chem, 2011 相似文献
10.
Henry W. Orton Dr. Jan Stanek Dr. Tobias Schubeis Dylan Foucaudeau Claire Ollier Dr. Adrian W. Draney Dr. Tanguy Le Marchand Dr. Diane Cala-De Paepe Prof. Dr. Isabella C. Felli Prof. Dr. Roberta Pierattelli Prof. Dr. Sebastian Hiller Dr. Wolfgang Bermel Dr. Guido Pintacuda 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(6):2400-2405