Intra-uterine particle–fluid motion through a compliant asymmetric tapered channel with heat transfer

Journal of Thermal Analysis and Calorimetry - In this article, the intra-uterine flow with small suspended particles under the impact of heat transfer is investigated. Intra-uterine fluid motion...     

Curvature measurement using phase shifting in-line interferometry,single shot off-axis geometry and Zernike's polynomial fitting

This paper describes the difference between phase shifting in-line interferometry, single shot off-axis geometry and Zernike's polynomial fitting methods for measuring the curvature of a spherical smooth surface by using the Michelson interferometer. In phase shifting in-line interferometry, four interferograms shifted by a piezoelectric actuator (PZT) were captured by a digital detector and corrected by using the flat fielding method. In off-axis geometry, single shot off-axis interferogram was obtained by tilting the reference and the object wave of the off-axis interferogram was reconstructed in the central region of the observation plane by using the digital reference wave concept. The demodulated phase map was obtained and unwrapped to remove the 2π ambiguity. The unwrapped phase map was converted to height and the sagittal length that used for curvature measurement was calculated accurately. The results extracted from phase shifting in-line interferometry and single shot off-axis geometry methods were compared with the results extracted from single shot Zernike's polynomial fitting method and the results were in excellent agreement. A new trial was done to overcome the fringes produced from the object interfaces. Some factors of uncertainty which affected on the measurement were estimated in the order of 6.0 × 10^?5 mm or 0.003 dioptre (▽).     

Performance enhancement of a DC-operated micropump with electroosmosis in a hybrid nanofluid: fractional Cattaneo heat flux problem

The purpose of this investigation is to theoretically shed some light on the effect of the unsteady electroosmotic flow (EOF) of an incompressible fractional second-grade fluid with low-dense mixtures of two spherical nanoparticles, copper, and titanium. The flow of the hybrid nanofluid takes place through a vertical micro-channel. A fractional Cattaneo model with heat conduction is considered. For the DC-operated micropump, the Lorentz force is responsible for the pressure difference through the microchannel. The Debye-Hükel approximation is utilized to linearize the charge density. The semi-analytical solutions for the velocity and heat equations are obtained with the Laplace and finite Fourier sine transforms and their numerical inverses. In addition to the analytical procedures, a numerical algorithm based on the finite difference method is introduced for the given domain. A comparison between the two solutions is presented. The variations of the velocity heat transfer against the enhancements in the pertinent parameters are thoroughly investigated graphically. It is noticed that the fractional-order parameter provides a crucial memory effect on the fluid and temperature fields. The present work has theoretical implications for biofluid-based microfluidic transport systems.

     

HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers

In this study, a sensitive high‐performance liquid chromatography method was developed and validated for the simultaneous determination of seven angiotensin II receptor blockers, namely, hydrochlorothiazide, chlorthalidone, eprosartan mesylate, valsartan, losartan potassium, irbesartan, and candesartan cilexetil. Different chromatographic parameters were tested and fully optimized. Best chromatographic separation was accomplished on a reversed‐phase octadecylsilyl column (250 × 4.6 mm id; 5 μm) under gradient elution using methanol/sodium phosphate monobasic buffer (0.01 M, pH 6.5) as mobile phase. The detection of target analytes was obtained at 254 nm. The pH of the buffer has been selected according to Marvin^® sketch software. The proposed method was validated according to ICH guidelines and showed good precision (relative standard deviation < 1), good linearity (square of correlation coefficient ≥ 0.999), and high accuracy (between 98 and 102%) with detection limit and quantitation limit (40 and 160 ng/mL, respectively) for all the detected analytes.     

Simulation of ion beam extraction and focusing system

The characteristics of ion beam extraction and focused to a volume as small as possible were investigated with the aid of computer code SIMION 3D version 7. This has been used to evaluate the extraction characteristics (accel-decel system) to generate an ion beam with low beam emittance and high brightness. The simulation process can provide a good study for optimizing the extraction and focusing system of the ion beam without any losses and transported to the required target. Also, a study of a simulation model for the extraction system of the ion source was used to describe the possible plasma boundary curvatures during the ion extraction that may be affected by the change in an extraction potential with a constant plasma density meniscus.     

Non-coherent noise reduction in digital holography based on root mean square technique

In this paper, the root mean square (rms) technique is applied in order to reduce the non-coherent noise in phase-contrast image. The proposed technique is applied to a sample of 200 μm step height nominally. The recorded off-axis interferograms generated from two different wavelengths are processed to obtain an object wave (amplitude and phase) for each wavelength separately. The independent phase maps are subtracted and a phase map for the beat-wavelength is obtained and converted to height map. The rms values of 10 pixels profiles from the obtained height map are calculated automatically to show the three-dimensional (3D) profile. The experimental results show that the non-coherent noise is reduced by the order of 90% when the rms technique is applied and the uncertainty in measurement has been found to be of the order of 1.5 μm. The proposed technique can provide a simple and real solution for measuring 3D objects having high abrupt height difference.     

Ion-acoustic solitary waves in a dense pair-ion plasma containing degenerate electrons and positrons

Fully nonlinear propagation of ion-acoustic solitary waves in a collisionless dense/quantum electron–positron–ion plasma is investigated. The electrons and positrons are assumed to follow the Thomas–Fermi density distribution and the ions are described by the hydrodynamic equations. An energy balance-like equation involving a Sagdeev-type pseudo-potential is derived. Finite amplitude solutions are obtained numerically and their characteristics are discussed. The small-but finite-amplitude limit is also considered and an exact analytical solution is obtained. The present studies might be helpful to understand the excitation of nonlinear ion-acoustic solitary waves in a degenerate plasma such as in superdense white dwarfs.     

Electrochemical,luminescent and photographic characterisation of cavitation

The characterisation of a small sonochemical reactor has been performed using electrochemical, luminescent and photographic techniques. The electrochemical experiments have employed a novel flow system to determine the formation of sonochemical products (in this case hydrogen peroxide) in semi-real time with high sensitivity. The rate of production of hydrogen peroxide is reported as a function of driving pressure amplitude. The degradation of an organic molecule, specifically the organic dye amaranth, within the sonochemical cell is also reported.     

SERS at structured palladium and platinum surfaces

Palladium and platinum are important catalytic metals, and it would be highly advantageous to be able to use surface enhanced Raman spectroscopy (SERS) to study reactive species and intermediates on their surfaces. In this paper we describe the use of templated electrodeposition through colloidal templates to produce thin (<1 microm) films of palladium and platinum containing close packed hexagonal arrays of uniform sphere segment voids. We show that, even though these films are not rough, when the appropriate film thickness and sphere diameter are employed these surfaces give stable, reproducible surface enhancements for Raman scattering from molecules adsorbed at the metal surface. We report SERS spectra for benzenethiol adsorbed on the structured palladium and platinum surfaces of different thicknesses and void diameters and show that, for 633 nm radiation, enhancements of 1800 and 550 can be obtained for palladium and platinum, respectively.     

Spectrofluorometric determination of verapamil hydrochloride in pharmaceutical preparations and human plasma using organized media: application to stability studies

A highly sensitive spectrofluorometric method was developed for the determination of verapamil hydrochloride (VP HCl) in pharmaceutical formulations and biological fluids. The proposed method is based on investigation of the fluorescence spectral behavior of VP HCl in micellar systems, such as sodium dodecyl sulfate (SDS) and beta-cyclodextrin (beta-CD). In aqueous solutions of borate buffer of pH 9 and 8.5, VP HCI was well incorporated into SDS and beta-CD, respectively, with enhancement of its native fluorescence. The fluorescence was measured at 318 nm after excitation at 231 nm. The fluorescence intensity enhancements were 183 and 107% in SDS and in beta-CD, respectively. The fluorescence-concentration plots were rectilinear over the range of 0.02-0.2 and 0.02-0.25 microg/mL, with lower detection limits of 5.58 x 10(-3) and 3.62 x 10(-3) microg/mL in SDS and beta-CD, respectively. The method was successfully applied to the analysis of commercial tablets and the results were in good agreement with those obtained with the official method. The method was further applied to the determination of VP HCl in real and spiked human plasma. The mean % recoveries in the case of spiked human plasma (n=4) was 92.59 +/- 3.11 and 88.35 +/- 2.55 using SDS and beta-CD, respectively, while that in real human plasma (n=3) was 90.17 +/- 6.93 and 89.17 +/- 6.50 using SDS and beta-CD, respectively. The application of the method was extended to the stability studies of VP HCl after exposure to ultraviolet radiation and upon oxidation with hydrogen peroxide.