亚硫酸钠介导的s4U转化检测转录组新生RNA中m6A

发展了亚硫酸钠介导的4-硫代尿苷(s⁴U)转化为胞苷(C)的方法, 用s⁴U标记新生RNA, 通过反应将s⁴U转化为C可成功检测新生RNA. 将新生RNA使用s⁴U标记后进行反应, 再使用m⁶A抗体对m⁶A片段进行富集, 从m⁶A中分析T到C突变位点便成功区分出含m⁶A的新生RNA. 该方法有希望应用于单个基因上m⁶A的动态变化检测, 有助于人们进一步了解m⁶A的修饰机制, 为m⁶A功能研究提供新的方法.     

苯乙烯-甲基丙烯酸十六酯的共聚及降焦研究

利用响应面分析法对聚苯乙烯-甲基丙烯酸十六酯吸油树脂吸附卷烟焦油和烟碱的影响因素进行分析,拟合树脂的单体组成、交联度与致孔剂用量与吸附率间的回归方程,绘制响应面分析图,得到聚合工艺最佳优化条件:单体组成为0.6、交联度0.8%、致孔剂用量9.8%,在最佳条件下,树脂对焦油和烟碱的吸附率分别为37.23%、15.26%,对烟气中多环芳烃吸附率可达80%以上,整个抽吸过程都有吸附效果.     

Track reconstruction in the BESⅢ muon counter

The reconstruction algorithm for BESⅢ Muon Counter, MucRecAlg, is developed with the objectoriented language C＋＋ in BESⅢ offine software environment. MucRecAlg consists of the following functions：to find track seeds either from extrapolation of tracks in the main drift chamber or from the fired strips in muon counter, to select fired strips associated to the candidate tracks, to fit the candidate tracks with a linear or quadratic function and to calculate other parameters of the tracks for muon identification. Monte Carlo samples are generated to check the performance of the reconstruction package, such as reconstruction effciency, muon remaining rate and pion rejection rate, etc. The preliminary results show that the pion rejection rate is around 3%—4% while the muon remaining rate is better than 90% in 0.4—1.6 GeV/c momentum region, which meets the requirement as shown in the design report.     

Decay vertex reconstruction and 3-dimensional lifetime determination at BESⅢ

This paper focuses mainly on the vertex reconstruction of resonance particles with a relatively long lifetime such as Ks^0, A, as well as on lifetime measurements using a 3-dimensional fit. The kinematic constraints between the production and decay vertices and the decay vertex fitting algorithm based on the least squares method are both presented. Reconstruction efficiencies including experimental resolutions are discussed. The results and systematic errors are calculated based on a Monte Carlo simulation.     

Study of BESⅢ MUC offine software with cosmic-ray data

Cosmic-ray data of 90 M events have been collected and used for calibration,alignment as well as detector tuning. A special tracking algorithm for the BESⅢ muon counter is developed and verified with Monte-Carlo simulation and then further confirmed with the cosmic-ray data. The obtained strip resolutions are in good agreement with the design values. A new alignment approach for the BESⅢ muon counter is confirmed with the cosmic-ray data and proposed to be used in future analysis of experimental data.