棉酚对大鼠血睾屏障的影响

用30mg/kg体重的醋酸棉酚喂大白鼠,从服药的第3周,即发现曲细精管的电位差由34℃时的对照值4.75±1.39mV降为 3.63±0.79mV,并且失去了电位差-温度之间的线性关系.服药至第5周时,硝酸镧可透入基底膜,进入上皮内和部分支持细胞紧密连接结构;服药8周后,硝酸镧可透过支持细胞的紧密连接结构,同时该区排列变为不规则.提示棉酚可导致血睾屏障功能障碍,从而破坏精子发育环境,这可能是棉酚抑制精子生成的主要原因之一。     

用于电响应红外反射窗的液晶聚合物薄膜特性研究

提出了一种红外反射器件,通过载体液晶在电场下的转向控制胆甾型液晶聚合物粒子在器件中的排布方向,实现红外反射与透射之间切换.其中,胆甾型液晶聚合物粒子是实现红外反射关键.介绍了胆甾型液晶聚合物薄膜的制备方法,并采用超声波破碎的方法制备液晶粒子.研究了液晶混合物中不同比例的交联剂液晶1对液晶聚合物薄膜脆性和反射波段的影响,发现当液晶1占100%时,液晶聚合物薄膜的脆性最大,且其清亮点最高,并且薄膜的反射波段随着液晶1比例的增加而向短波方向偏移.同时,研究了薄膜厚度对液晶聚合物粒子的影响,发现液晶薄膜厚度越小,制备的液晶聚合物粒子越小且越均匀,其制成的器件电驱动性更好.该研究有利于帮助电响应红外反射窗的性能优化.     

EFFECT OF GOSSYPOL ON THE POTENTIAL DIFFERENCE OF RAT SEMINIFEROUS TUBULES

The p.d. of the rat seminiferous tubules was 4.75±1.39 mV (lumen negative) at 35℃ and varied linearly with temperatures from 26 to 40℃.A depolarization of the seminiferous tubules was found in the rats administered with gossypol at the dosage of 30 mg/kg body weight for 3 weeks, the p.d. lowered to 3.63±0.79 mV at 35℃ and was independent of the changes of seminiferous tubules temperature. In the 5-week-gossypol-treatment group, the tracer penetrated not only the myoid cell layer, but also went beyond the tight junction complexes between Sertoli cells. The lanthanum appeared in the cleft surrounding spermatogonia. In the 8-week-gossypol-treatment group, the lanthanum was found in the adluminal compartment.It indicates that gossypol can cause a dysfunction of the Sertoli cells and blood-testis barrier and disturb a good physiological environment for the developing spermatecytes.