全文获取类型
收费全文 | 1162篇 |
免费 | 36篇 |
国内免费 | 12篇 |
专业分类
化学 | 738篇 |
晶体学 | 14篇 |
力学 | 30篇 |
数学 | 235篇 |
物理学 | 193篇 |
出版年
2023年 | 3篇 |
2022年 | 4篇 |
2021年 | 17篇 |
2020年 | 9篇 |
2019年 | 16篇 |
2018年 | 15篇 |
2017年 | 18篇 |
2016年 | 51篇 |
2015年 | 49篇 |
2014年 | 37篇 |
2013年 | 66篇 |
2012年 | 71篇 |
2011年 | 65篇 |
2010年 | 45篇 |
2009年 | 56篇 |
2008年 | 73篇 |
2007年 | 66篇 |
2006年 | 88篇 |
2005年 | 76篇 |
2004年 | 64篇 |
2003年 | 51篇 |
2002年 | 43篇 |
2001年 | 16篇 |
2000年 | 11篇 |
1999年 | 14篇 |
1998年 | 10篇 |
1997年 | 9篇 |
1996年 | 16篇 |
1995年 | 9篇 |
1994年 | 9篇 |
1993年 | 7篇 |
1992年 | 10篇 |
1991年 | 8篇 |
1990年 | 5篇 |
1989年 | 3篇 |
1988年 | 6篇 |
1987年 | 11篇 |
1986年 | 7篇 |
1985年 | 9篇 |
1984年 | 6篇 |
1983年 | 6篇 |
1982年 | 10篇 |
1981年 | 5篇 |
1980年 | 8篇 |
1979年 | 2篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1880年 | 1篇 |
排序方式: 共有1210条查询结果,搜索用时 15 毫秒
1.
Antonio R. Montoro Bustos Marta Garcia-Cortes Hector González-Iglesias Jorge Ruiz Encinar José M. Costa-Fernández Miguel Coca-Prados Alfredo Sanz-Medel 《Analytica chimica acta》2015
A generic strategy based on the use of CdSe/ZnS Quantum Dots (QDs) as elemental labels for protein quantification, using immunoassays with elemental mass spectrometry (ICP-MS), detection is presented. In this strategy, streptavidin modified QDs (QDs-SA) are bioconjugated to a biotinylated secondary antibody (b-Ab2). After a multi-technique characterization of the synthesized generic platform (QDs-SA-b-Ab2) it was applied to the sequential quantification of five proteins (transferrin, complement C3, apolipoprotein A1, transthyretin and apolipoprotein A4) at different concentration levels in human serum samples. It is shown how this generic strategy does only require the appropriate unlabeled primary antibody for each protein to be detected. Therefore, it introduces a way out to the need for the cumbersome and specific bioconjugation of the QDs to the corresponding specific recognition antibody for every target analyte (protein). Results obtained were validated with those obtained using UV–vis spectrophotometry and commercial ELISA Kits. 相似文献
2.
3.
4.
5.
6.
James D. Mattock Dr. Alfredo Vargas Dr. Rian D. Dewhurst 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(47):16968-16974
The effect of carbenes as Lewis donor groups on the homoaromaticity of mono‐ and bicyclic organic molecules is surveyed. The search for viable carbene‐stabilised homoaromatics resulted in a large amount of rejected candidates as well as nine promising candidates that are further analysed for their homoaromaticity by using a number of metrics. Of these, five appeared to show modest homoaromaticity, whereas another compound showed a level of homoaromaticity comparable with the homotropylium cation benchmark compound. Isoelectronic analogues and constitutional isomers of the lead compound were investigated, however, none of these showed comparable homoaromaticity. The implications of these calculations on the design of donor‐stabilised homoaromatics are discussed. 相似文献
7.
Claudia González de Vega Cesar Álvarez Llamas Nerea Bordel Rosario Pereiro Alfredo Sanz-Medel 《Analytica chimica acta》2015
The analytical capabilities of a glow discharge (GD) as a secondary source for excitation/ionization of the material provided by laser ablation (LA) have been compared to conventional laser induced breakdown spectroscopy (LIBS). In LA–GD both sources can be independently adjusted to optimize the sampling process and then its subsequent excitation. This could involve a number of analytical performance advantages, such as reduced matrix dependence, greater precision and sensitivity than those encountered in LIBS. For such purpose, an ablation chamber design including two electrodes to generate the GD discharge has been built and assayed. A comparison between LIBS and LA–GD–OES has been carried out, both, under reduced argon and helium atmospheres. Different sets of samples (conducting reference materials, glass and fluorine pellets) have been used to evaluate the novel coupled technique. The LA–GD coupled system has shown to provide lower detection limits. In addition, best linear correlations between intensities and concentrations and lower matrix effects have also been found using the coupled system. Moreover, special advantages of the LA–GD–OES have also been demonstrated for the analysis of fluorine. 相似文献
8.
9.
10.
Dr. Tatiana Suárez-Rodríguez Prof. Dr. Ángel L. Suárez-Sobrino Prof. Dr. Alfredo Ballesteros 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(51):13079-13084
Gold(I)-catalyzed formal [4+2] cycloaddition of O-aryl ynol ethers 1 and enol ethers 2 is described. This intermolecular reaction between two electron-rich unsaturated systems takes place, under mild conditions, in the presence of 5 mol% [IPrAu(CH3CN)]SbF6 as catalyst giving chromene derivatives with good yields. The cycloaddition is completely regio- and stereoselective, as well as versatile for both reactives. Silyl enol ethers can also react in the same way and under the same reaction conditions with quantitative yields. A plausible mechanism through a selective addition of the enol ether to the alkyne gold activated complex followed by an intramolecular aromatic electrophilic substitution is proposed. Several experimental results support the presence of a cationic oxonium intermediate prior to the aromatic substitution. The reaction represents a new entry to the chromene core. 相似文献