全文获取类型
收费全文 | 587篇 |
免费 | 56篇 |
国内免费 | 38篇 |
专业分类
化学 | 399篇 |
晶体学 | 4篇 |
力学 | 16篇 |
数学 | 24篇 |
物理学 | 238篇 |
出版年
2023年 | 7篇 |
2022年 | 4篇 |
2021年 | 10篇 |
2020年 | 8篇 |
2019年 | 16篇 |
2018年 | 28篇 |
2017年 | 13篇 |
2016年 | 13篇 |
2015年 | 26篇 |
2014年 | 29篇 |
2013年 | 42篇 |
2012年 | 63篇 |
2011年 | 68篇 |
2010年 | 41篇 |
2009年 | 35篇 |
2008年 | 36篇 |
2007年 | 29篇 |
2006年 | 16篇 |
2005年 | 20篇 |
2004年 | 20篇 |
2003年 | 12篇 |
2002年 | 12篇 |
2001年 | 12篇 |
2000年 | 12篇 |
1999年 | 9篇 |
1998年 | 9篇 |
1997年 | 9篇 |
1996年 | 8篇 |
1995年 | 3篇 |
1994年 | 4篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 4篇 |
1989年 | 2篇 |
1988年 | 4篇 |
1987年 | 8篇 |
1986年 | 2篇 |
1985年 | 4篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1975年 | 3篇 |
1974年 | 7篇 |
1973年 | 5篇 |
1972年 | 2篇 |
1970年 | 2篇 |
1968年 | 1篇 |
1967年 | 5篇 |
排序方式: 共有681条查询结果,搜索用时 15 毫秒
1.
Raju Suresh Kumar Abdulrahman I. Almansour Natarajan Arumugam D. Kotresha J. Carlos Menéndez Raju Ranjith Kumar 《Journal of heterocyclic chemistry》2021,58(2):580-588
A three-component, [3 + 2]-cycloaddition/annulation domino protocol is described for the synthesis in excellent yield of a polycyclic cage-like heterocyclic hybrid (PCHH) that comprises various advantaged structural units viz., α,β-unsaturated ketone moiety, 4-pyridinone and pyrroloisoquinoline in a cage-like framework. The antitumor activity of PCHH on human breast (MCF7), colon (HCT116), cervical (JURKAT) and lung (NCI-H460) malignant cell lines inhibited the propagation of all cell lines. This hybrid molecule displayed increased broad-spectrum anticancer activity with higher doses of PCHH. Furthermore, the compound induced 45.21% of early apoptosis and 46.32% of late apoptosis in the Jurkat cancer cell line. Cell cycle analysis showed that this cage-like compound caused cell cycle arrest of Jurkat cells at the S phase and sub G0/G1 phase. Additionally, it led to increased DNA fragmentation and mitochondrial membrane permeabilization through activation of caspase-3 enzyme. Present investigation demonstrates the specific cytotoxic activity of the cage-like compound and the induction of apoptosis through the intrinsic pathway of Jurkat cells. 相似文献
2.
3.
4.
Unmasking the Action of Phosphinous Acid Ligands in Nitrile Hydration Reactions Catalyzed by Arene–Ruthenium(II) Complexes 下载免费PDF全文
Dr. Eder Tomás‐Mendivil Dr. Victorio Cadierno Dr. María I. Menéndez Dr. Ramón López 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(47):16874-16886
The catalytic hydration of benzonitrile and acetonitrile has been studied by employing different arene–ruthenium(II) complexes with phosphinous (PR2OH) and phosphorous acid (P(OR)2OH) ligands as catalysts. Marked differences in activity were found, depending on the nature of both the P‐donor and η6‐coordinated arene ligand. Faster transformations were always observed with the phosphinous acids. DFT computations unveiled the intriguing mechanism of acetonitrile hydration catalyzed by these arene–ruthenium(II) complexes. The process starts with attack on the nitrile carbon atom of the hydroxyl group of the P‐donor ligand instead of on a solvent water molecule, as previously suggested. The experimental results presented herein for acetonitrile and benzonitrile hydration catalyzed by different arene–ruthenium(II) complexes could be rationalized in terms of such a mechanism. 相似文献
5.
6.
A system of boundary integral equations that allows evaluating the displacement and stress fields for an interfacial crack
under harmonic loading is presented. Expressions for the integral kernels are obtained. A numerical solution for a penny-shaped
crack between steel and aluminum half-spaces under normally incident compression-rarefaction wave is given
__________
Translated from Prikladnaya Mekhanika, Vol. 43, No. 8, pp. 47–56, July 2007. 相似文献
7.
考虑费米子的反常磁矩, 运用赝势法和热力学理论, 导出弱磁场中弱相互作用费米气体自由能的解析式, 以此为基础给出高温和低温情况下系统热力学性质, 分析反常磁矩对热力学性质的影响机理. 研究表明: 反常磁矩对热力学性质的影响与温度相关, 而且这种影响随温度的上升在低温区是增大的, 在高温区是减小的; 对于系统的化学势、内能, 反常磁矩加强了磁场的影响, 弱化了相互作用的影响; 对于系统的热容量, 反常磁矩在低温区使其减小, 在高温区使其增加. 相似文献
8.
Jaroslav Menčík 《Meccanica》2007,42(1):19-29
The paper reviews the current state of the depth-sensing indentation (sometimes called nanoindentation), where the information
on material behaviour and properties is obtained from the indenter load and depth, measured continuously during loading and
unloading. It is shown how the contact parameters and principal characteristics are determined using pointed or spherical
indenters. Indentation tests can be used for the measurement of hardness and elastic modulus, and also of the yield stress
and for the construction of stress–strain diagrams, for the determination of the work of indentation and its components. Most
devices use monotonic loading and unloading, but some also enable measurement under a small harmonic signal added to the basic
monotonously increasing load. This makes possible continuous measurement of contact stiffness and the study of dynamic properties
and the determination of properties of coatings. One section is devoted to the measurement on viscoelastic-plastic materials,
where the delayed deforming must be considered during the measurement as well as in data evaluation. Instrumented indentation
can also be used for the study of creep under high temperatures. The paper also discusses the errors arising in depth-sensing
measurements and informs briefly about some other possibilities of the method. 相似文献
9.
Deep desulfurization by oxidation using an active ionic liquid‐supported Zr metal–organic framework as catalyst 下载免费PDF全文
Jianxiang Wu Yilong Gao Wei Zhang Yueyue Tan Aomin Tang Yong Men Bohejin Tang 《应用有机金属化学》2015,29(2):96-100
In this study, a Zr metal–organic framework (UIO‐66) was synthesized with zirconium tetrachloride and terephthalic acid using the solvent method. Then various masses of 1‐methylimidazolium‐3‐propylsulfonate hydrosulfate (PSMIMHSO4) were supported on the UIO‐66 as catalysts, which were used for catalytic oxidative desulfurization. Sulfur removal using 400 mg of 40% PSMIMHSO4 supported on the UIO‐66 of greater than 94% was obtained at 313 K for 20 min with an O/S molar ratio of 7:1. The results obtained in this work could provide useful information for the design of water‐stable metal–organic frameworks with permanent porosity in applications of catalytic oxidative desulfurization. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
10.
Natalia Rey-Raap J. Angel Menéndez Ana Arenillas 《Journal of Sol-Gel Science and Technology》2014,69(3):488-497
Carbon xerogels (CX) can be synthesized by microwave-assisted heating. The transfer of this technology to an industrial scale passes through the optimization of the variables that affect the process. The effect of the main operational variables, i.e., initial volume of the precursor, gelation and ageing time and temperature of the synthesis, on the final porous properties of CX has been evaluated. It was found that the development of porosity in the CX synthesised in the microwave oven is hardly influenced by the increase in the initial volume of the precursor solution. This suggests that it is feasible to scale up the production of these materials by means of microwave heating. Furthermore, the consumption of energy does not increase in proportion to the volume of xerogel synthesized. Thus, the process is energy efficient, saves a considerable amount of time and requires only a single device to carry it out. These advantages, along with the fact that a temperature variation of 10 °C is not determinative in the xerogels’ final properties, indicate that CX could be produced on a large scale in a cost effective way . 相似文献