Chemoenzymatic Synthesis of 2-Arachidonoylglycerol, An Endogenous Ligand for Cannabinoid Receptors

A simple and efficient synthesis of 2-arachidonoyl glycerol, an endogenous agonist for cannabinoid receptors was achieved using Novozym 435, immobilized lipase from Candida antarctica.     

Elastic differential cross sections and analyzing powers for p+40,42,44,48Ca at 0.8 GeV

Differential cross sections and analyzing powers for the elastic scattering of 800 MeV polarized protons from ^40,42,44,48Ca are reported. A first-order, spin-dependent KMT optical potential analysis is presented from which the rms radii of the neutron densities are deduced. A comparison of these results with other determinations and with various theoretical predictions is given.     

Spin observables in small-angle elastic → d scattering with an L-type deuteron target at 800 MeV

We have measured spin correlation parameters that describe the elastic scattering of 800 MeV polarized protons from an L-type polarized deuteron target at laboratory angles below 20°. The measured parameters include the correlated analyzing powers A_SL, A_LL and A_NLL and the proton spin-transfer coefficients C_0L,S, C_0L,L, C_SL,N, C_NL,S, C_NL,L and C_LL,N. The results are compared with single-scattering predictions based on different phase-shift solutions for the nucleon-nucleon scattering matrix.     

Measurement of the spin correlationA ookk innp elastic scattering between 0.63 and 1.08 GeV

We present the measurements of the spin correlation parameterA _ookk (np). A longitudinally polarized beam of free neutrons obtained from the break-up of polarized deuterons was scattered on the longitudinally polarized Saclay frozen-spin proton target. Measurements were carried out at SATURNE II, at neutron beam kinetic energies of 0.63, 0.88, 0.98 and 1.08 GeV. The data points cover the angular region from about 40° to 110° CM. The observed angular dependence ofA _ookk (np) at 0.63 GeV agree with the phase shift analysis predictions except at small angles.     

Ion-molecule reactions of a metalloporphyrin with common perfluoro mass standards

The ruthenium porphyrin carbonyl (I) reacts with perfluorokerosene and perfluorotributylamine to give ions of the type [M – CO + C_nF_2n], n = 1 to 4.     

A direct measurement of the total proton decay width of an isobaric analog state

Differential cross sections for the ²⁰⁸Pb (p, n) reaction populating the isobaric analog state (IAS) of the ²⁰⁸Pb ground state in ²⁰⁸Bi have been measured at a proton bombarding energy of 30.5 MeV. The experimental technique utilized the proton (p?) decay of the IAS to obtain neutron time-of-flight spectra. When these differential cross sections are compared to those obtained for the same reaction at 30.5 MeV using the pulsed-beam technique to obtain neutron time-of-flight spectra, the percentage of the IAS decay through p? channels is obtained. This comparison indicates that the p? decay of the IAS to the first three states of ²⁰⁷Pb accounts for almost all of the IAS width (0.97±0.28).     

Photochemistry and Photophysical Properties of Novel, Unsymmetrically Substituted Metallophthalocyanines

Abstract— A series of novel, unsymmetrically substituted metallophthalocyanines was synthesized, along with their symmetrically substituted analogs, and the effects of structure and metal substitution on their photophysical and photoredox properties were investigated. The macrocy-cles were synthesized using a mixed-condensation method followed by chromatographic separation of the resulting soluble products. They possess a catechol "active site" and three tert-butyl groups for enhanced solubility. The ground- and excited-state photophysical properties of the free-base, Zn(II) and Pd(II) macrocycles were measured and compared with their symmetrically substituted (tetra[ tert -butyl]) analogs. The efficiency with which these macrocycles sensitize the formation of singlet oxygen was determined and discussed in the context of the excited-state photophysical properties. Several examples of photoinduced electron transfer reactions with one- and two-electron acceptors are demonstrated and discussed. These soluble molecules can be tuned to optimize their photochemical and redox properties by varying the central metal, axial ligands and other substituents, thereby providing a series of molecules for the investigation of photodynamic therapy and photoinduced electron transfer mechanisms.     

Chemisorption of hydrogen on titanium: Embedding theory and comparisons with small clusters

The chemisorption of H₂ on Ti(0001) is treated using an ab initio CI theory for the surface region. Dissociation of H₂ occurs above the surface but more stable 3-fold coordination sites lie closer to the surface at ～ 1.3 Å. Adsorption in adjacent 3-fold sites is less stable than in separated sites sharing only one surface atom. The calculated adsorption energy of 45 kcal/mol H₂ compares favorably with experiment. Bonding involves mainly the 4s electrons of the metal leading to hydridic hydrogens and a polarized lattice electron distribution, but d bonding and correlation effects significantly increase the binding energy. Calculations on small metal clusters also show dissociative adsorption but much larger hydrogen binding energies are obtained.