ZnBr2 catalyzed domino Knoevenagel-hetero-Diels–Alder reaction: An efficient route to polycyclic thiopyranoindol annulated [3,4-c]quinolone derivatives

Various novel polycyclic thiopyranoindol annulated [3,4-c]quinolone derivatives were synthesized via domino Knoevenagel-hetero-Diels–Alder reactions of indoline-2-thions and novel N-acrylated anthranilaldehydes in refluxing ethanol as a solvent in the presence of 20 mol% ZnBr₂ as a Lewis acid catalyst. All reactions proceed with high yields with excellent regio- and stereoselectivity.     

Amplified cathodic electrochemiluminescence of luminol based on zinc oxide nanoparticle modified Ni-foam electrode for ultrasensitive detection of amoxicillin

Journal of Solid State Electrochemistry - Here is reported a new feasible and facile method for the determination of amoxicillin by the electrochemiluminescence (ECL) method. The ECL signal was...     

Investigation of MHD effect on nanofluid heat transfer in microchannels

Journal of Thermal Analysis and Calorimetry - An incompressible preconditioned lattice Boltzmann method (IPLBM) is proposed to investigate the fluid flow and heat transfer characteristics of...     

Effects of composition and transparency on photo and radioluminescence of Y2O3:Eu complexes

A solid state-based method using a hot reaction chamber is applied to the synthesis of Y₂O₃:Eu particles containing Eu from 0 to 5 mol%. The produced powders are studied using X-ray diffraction (XRD), scanning electron microscopy and transmission electron microscopy (TEM), as well as photoluminescence (PL) and radioluminescence tests. TEM and XRD results revealed the powder to be mono-disperse and in the form of a solid solution. The PL of Y₂O₃:Eu powder depends on both the concentration quenching effect (due to an excess of Eu concentration) and the surface luminescence effect (depicted by a higher surface area induced by the large phosphor concentration in the solution or smaller particle sizes). A ²²Na gamma source is used to compare the recorded count rates for four Y₂O₃:Eu scintillator materials with different concentrations of Eu. Each scintillator composition is examined in four forms: solid pellets with a high volume porosity and three aqueous solutions of Y₂O₃:Eu particles of the different scintillator materials at concentrations of 25, 50 and 100 mg/mL. The radioluminescence results indicated that increasing the transparency and/or the amount of Eu mol% of the scintillators increases the net average counts.     

Development of a Novel Electrochemical Biosensor for Detection and Discrimination of DNA Sequence and Single Base Mutation in dsDNA Samples Based on PNA‐dsDNA Hybridization – a new Platform Technology

In spite of the extensive attention paid on the development of various DNA detection strategies, very few studies have been reported regarding direct detection of DNA sequence and mutation in dsDNA. Here, we describe the feasibility of detection and discrimination of target DNA sequences and single base mutations (SBM) directly in double‐stranded oligonucleotides and PCR products without the need for denaturation of the target dsDNA samples. This goal was achieved by employing a peptide nucleic acid (PNA) chain, self‐assembled on the gold electrode as a probe, which binds to dsDNA and forms PNA‐dsDNA hybrid.