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正常组织和胰腺癌组织中差异表达蛋白的鉴定 总被引:2,自引:2,他引:0
采用双向凝胶电泳和生物质谱技术, 对12对胰腺癌组织和癌旁组织样品、3个胰腺良性疾病样品、3个正常胰腺组织样品的蛋白质进行了分离和鉴定, 获得了重复性较好的双向凝胶电泳图谱; 鉴定了胰腺癌和癌旁组织的差异表达蛋白质, 发现了30个差异表达蛋白质; 应用MALDI-TOF-MS/MS技术对差异表达蛋白质进行鉴定, 共有24个蛋白质得到鉴定, 其中15个蛋白质在胰腺癌组织中表达上调, 9个蛋白质表达下调. 这些蛋白质与胰腺癌的发生相关, 可能成为胰腺癌的分子标志物和药物治疗的靶蛋白. 相似文献
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以广州东镜新城一期会所梁粘贴碳纤维为例,对碳纤维施工过程中的施工材料、工艺及质量控制、施工组织、质量保证、安全措施等进行了阐述和总结。 相似文献
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Nonparaxial propagation of radially polarized chirped Airy beams in uniaxial crystal orthogonal to the optical axis 下载免费PDF全文
The nonparaxial propagation of radially polarized chirped Airy beams(RPCAiBs) in uniaxial crystal orthogonal to the optical axis is analytically studied. The effects of the first and the second order chirp factors, and the ratio of the extraordinary refractive index to the ordinary refractive index on the nonparaxial evolution of RPCAi Bs in different observation planes are investigated in detail. The results show that when one parameter changes, different components behave differently, and even the same component has various behavior in different directions. The initial slope of RPCAi Bs in the x-direction varies more with the first order chirp factor than that in the y-direction. Meanwhile, with the second order chirp factor becoming larger, the depth of the focus of the y-component in the x-direction decreases while that in the y-direction has no difference. In addition, the different ratios of the extraordinary refractive index to the ordinary refractive index change the difference of the depth of the focus between the x-and the y-components. 相似文献
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本文通过引入可变动目标函数的预规划来求线性的初始基可行解,可以大量减少外额变量的个数,从而简化了二阶段单纯形法,使之便于在计算机上实现。 相似文献
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