排序方式: 共有12条查询结果,搜索用时 15 毫秒
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Requejo-Isidro J McGinty J Munro I Elson DS Galletly NP Lever MJ Neil MA Stamp GW French PM Kellett PA Hares JD Dymoke-Bradshaw AK 《Optics letters》2004,29(19):2249-2251
We report the development of a high-speed wide-field fluorescence-lifetime imaging (FLIM) system that provides fluorescence-lifetime images at rates of as many as 29 frames/s. A FLIM multiwell plate reader and a potentially portable FLIM endoscopic system operating at 355-nm excitation have been demonstrated. 相似文献
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João Lagarto Jonathan D. Hares Christopher Dunsby Paul M. W. French 《Journal of fluorescence》2017,27(5):1643-1654
Autofluorescence lifetime measurements, which can provide label-free readouts in biological tissues, contrasting e.g. different types and states of tissue matrix components and different cellular metabolites, may have significant clinical potential for diagnosis and to provide surgical guidance. However, the cost of the instrumentation typically used currently presents a barrier to wider implementation. We describe a low-cost single point time-resolved autofluorescence instrument, exploiting modulated laser diodes for excitation and FPGA-based circuitry for detection, together with a custom constant fraction discriminator. Its temporal accuracy is compared against a “gold-standard” instrument incorporating commercial TCSPC circuitry by resolving the fluorescence decays of reference fluorophores presenting single and double exponential decay profiles. To illustrate the potential to read out intrinsic contrast in tissue, we present preliminary measurements of autofluorescence lifetime measurements of biological tissues ex vivo. We believe that the lower cost of this instrument could enhance the potential of autofluorescence lifetime metrology for clinical deployment and commercial development. 相似文献
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J. K. Brooks Kazuyuki Saitô JD Maitland Wright 《Rendiconti del Circolo Matematico di Palermo》2003,52(1):5-14
LetA be aC*-algebra with second dualA″. Let (φ
n)(n=1,...) be a sequence in the dual ofA such that limφ
n(a) exists for eacha εA. In general, this does not imply that limφ
n(x) exists for eachx εA″. But if limφ
n(p) exists whenever p is the range projection of a positive self-adjoint element of the unit ball ofA, then it is shown that limφ
n(x) does exist for eachx inA″. This is a non-commutative generalisation of a celebrated theorem of Dieudonné. A new proof of Dieudonné’s theorem, for
positive measures, is given here. The proof of the main result makes use of Dieudonné’s original theorem. 相似文献
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Fluorescence lifetime imaging with picosecond resolution for biomedical applications 总被引:5,自引:0,他引:5
Dowling K Dayel MJ Lever MJ French PM Hares JD Dymoke-Bradshaw AK 《Optics letters》1998,23(10):810-812
We describe a novel whole-field fluorescence lifetime imaging system, based on a time-gated image intensifier and a solid-state laser oscillator-amplifier, that images lifetime differences of less than 10 ps. This system was successfully applied to discrimination between biological tissue constituents. 相似文献
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The eigen frequencies of radial pulsations of neutron stars are calculated in a strong magnetic field. At low densities we
use the magnetic BPS equation of state (EOS) similar to that obtained by Lai and Shapiro while at high densities the EOS obtained
from the relativistic nuclear mean field theory is taken and extended to include strong magnetic field. It is found that magnetized
neutron stars support higher maximum mass whereas the effect of magnetic field on radial stability for observed neutron star
masses is minimal. 相似文献
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